The GuardianUK News & Comment• 1 min read

Cravings ‘like heroin withdrawal’: what happens when weight-loss drugs don’t work?

Published 7 September 2026, 4:00pm

GLP-1 medications have been a gamechanger in the fight against obesity. But for a minority of patients, their impact is negligible. Why? When Mercedes was told by her doctor that she could be prescribed GLP-1 weight loss jabs in 2024, she broke down.

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